Bradykinin Storms and Covid Inflammation


We’re getting close to a year of living with Covid-19, but work is still ongoing to understand the mechanisms behind some of its most devastating effects. A lot of attention has been given to Cytokine Storms in this realm, but with some conflicting evidence there, Bradykinin Storms are starting to share some of the spotlight.

Sources:

https://jamanetwork.com/journals/jama/article-abstract/2770484
https://european-biotechnology.com/up-to-date/latest-news/news/roches-il-6-receptor-blocker-fails-in-phase-iii.html
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202000967
https://www.cdc.gov/coronavirus/2019-ncov/covid-data/investigations-discovery/hospitalization-death-by-race-ethnicity.html
https://elemental.medium.com/a-supercomputer-analyzed-covid-19-and-an-interesting-new-theory-has-emerged-31cb8eba9d63
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2769237
https://clinicaltrials.gov/ct2/show/NCT04488081

Related HCT episodes:
Covid is Not the Flu: https://youtu.be/J3W3xsbOlk4

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