Vitamin C, 100% L-Ascorbic Acid, USP, Ultrafine powder is a water soluble antioxidant. Vitamin C, a potent, naturally occurring antioxidant is an important constituent of skin. It plays a pivotal role in the prevention of dry skin and wrinkles, collagen synthesis and skin regeneration. Ascorbate is found in all layers of the skin, but is more concentrated in the epidermis than the dermis. However, it is readily depleted by about two thirds in cutaneous tissue stores with exposure to UV light. Biochemically, the body relies on ascorbate in the collagen biosynthetic pathway. It functions as a cofactor for two enzymes, lysyl and prolyl hydroxylases. These are dependent on iron and Vitamin C prevents iron oxidation and thus inactivation of these hydroxylases, thereby maintaining their activity.
Vitamin C has been shown to be effective in increasing collagen deposits and also enhancing collagen lattice contractions, implying that exogenous Vitamin C application contributes to strengthening the collagen framework and maintaining a healthy dermis. Topical application of Vitamin C has been shown to reduce the appearance of fine lines and wrinkles. Caused by mechanisms supporting collagen production, this leads to improving the appearance of the skin. It has further been proven to reduce the severity of sunburns and age spots.
Cutaneous levels of Vitamin C cannot be achieved well by ingestion, hence topical application is essential for preventing oxidative damage resulting from pollution, smoke and sunlight. Its use has been shown to increase generation of stratum corneum barrier lipids and stabilize lipid profiles, in particular glucosphingolipids and ceramides.